比较安全、疗效和成本效益的苯甲酸苄酯,氯菊酯,伊维菌素在疥疮患者。

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Bachewar NP、Thawani VR、马里SN, Gharpure KJ, Shingade VP, Dakhale GN

比较安全、疗效和成本效益的苯甲酸苄酯,氯菊酯,伊维菌素在疥疮患者。

印度J杂志。2009年2月,41 (1):9-14。doi: 10.4103 / 0253 - 7613.48882。

PubMed ID

20177574 (在PubMed

]

文摘

目的:比较三个在疥疮治疗方法安全、功效,在当地的人口和经济的那格浦尔。材料与方法:这是一个潜在的,随机的,比较临床试验在103年进行的参与者,随机分配到三组。第一组接受苯甲酸苄酯乳液(BB) 25%,第二组收到氯菊酯5%奶油,而第三组收到平板电脑伊维菌素200杯/公斤为一个单一的剂量。参与者被召回一周后随访评估。如果没有治愈的迹象,相同的干预是重复。两周的随访参与者治愈率,药物不良反应(ADR)监测,和postintervention观察。后续两周后停止。统计:费舍尔的确切的测试使用图垫Instat v 3.05。结果:伊维菌素治疗两周后显示,100%治愈率。氯菊酯减少瘙痒一周结束时的76%,治愈率明显优于伊维菌素。 At the end of two weeks treatment, this finding was reversed, that is, cure rate in ivermectin group was 100%. For cost-effectiveness analysis, treatment regimens were formulated hypothetically for comparison from Markov population tree for decision analysis. It was found that BB and ivermectin each consecutively for two weeks were most cost effective regimens giving complete cure in four weeks, while ivermectin was the fastest regimen giving the same results in two weeks. CONCLUSION: Benzyl benzoate as first line intervention and ivermectin in the remaining gave best cost-effective results in the study patients of scabies.

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药物

苯甲酸苄酯