硫酸镁治疗对新生儿的影响骨骼异常。

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Maeda松田Y, Y, Ito M, Sakamoto H, Masaoka N,高田M,佐藤K

硫酸镁治疗对新生儿的影响骨骼异常。

44 Gynecol。投资。1997;(2):82 - 8。

PubMed ID

9286718 (在PubMed

]

文摘

目的:据报道,新生儿骨骼异常发生由于长期静脉镁管理(MgSO4)孕妇。这项回顾性研究的目的是评估的频率异常和母亲和新生儿的临床背景。患者和方法:我们回顾了孕产妇(114例)和新生儿(139例)图表从所有孕妇接受静脉注射MgSO4管理早产与子痫前期6月1日,1992年和1994年5月31日。胸部x光片电影都获得出生后48小时内,医生不知道看过的临床数据。射线可透过的横向metaphyseal乐队的近端肱骨视为异常。受试者分为影响(组1和1)和影响(组2和2)组。新生儿出生在同一时期,孕妇没有MgSO4被认为是控制。结果:骨畸形的总数在母亲的后代接受MgSO4达13 (11.4%)。1组由13例,2组101例。对照组(p < 0.05),并未观察到骨异常。 Significant differences were found between groups 1 and 2 in the gestational ages at the start of MgSO4 administration and at delivery, and in the total duration of administration and doses of MgSO4. Also, cases of multiple pregnancy and pregnancy complicated with impaired glucose tolerance were more prevalent in group 1. According to the results obtained from 139 neonates, cases showing low Apgar and high magnesium score and those receiving respiratory support were more noticeable in group 1a (15 cases). CONCLUSIONS: The gestational ages and the total doses of MgSO4 in pregnant women were the main factors related to the onset of neonatal bone abnormalities, but other factors also have a possible bearing on the condition. In addition, the cases with onset of bone abnormality seemed to be associated with symptoms attributable to hypermagnesemia of neonates.

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药物

硫酸镁