舍曲林过量。

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刘GT,霍洛维茨

舍曲林过量。

阿德莱德大学地中海紧急情况。1996年2月,3 (2):132 - 6。doi: 10.1111 / j.1553-2712.1996.tb03400.x。

PubMed ID

8808373 (在PubMed

]

文摘

目的:确定临床表现症状和体征认为过量的舍曲林,最近批准的抗抑郁药。方法:前瞻性研究涉及五个西部地区中毒控制中心进行评估的临床表现推测舍曲林吞食(过量)。电话信息与舍曲林吞食被记录在标准数据收集形式。数据包括受年龄、性别、摄取,coingestants,评价时间间隔,生命体征、症状和体征,心电图异常,治疗,性格,和长度在艾德在9个月期间的收集。结果:42吞食的报道,两人的不良反应正常剂量和40是过量的。表示数量的舍曲林摄入50至8000毫克不等(平均1579毫克)。意味着病人年龄为35.3岁(范围1到69年)。平均间隔表示是3.0小时。十七岁的40个病人摄入舍曲林孤单。这个群,十没有迹象或症状。 The most common abnormalties reported in isolated sertraline overdose were tremor, lethargy, and nausea. Less common findings included agitation, confusion, and vomiting. There was no significant morbidity in this subgroup of presumed isolated sertraline ingestion. Of the 23 patients who ingested other medications along with sertraline, four were asymptomatic. Benzodiazepines and alcohol were the most frequently coingested substances. Lethargy, nausea, dry mouth, and mydriasis were the most common features reported in this group. Treatment included lavage, activated charcoal, and observation. Twelve patients were admitted for 24-hour observation, none had an adverse outcome. Of the patients released from the ED, the mean length of stay was 3.9 hours. CONCLUSION: Sertraline is commonly taken in overdose with other medications or alcohol. The signs and symptoms that develop in association with an overdose of sertraline appear to be minor and of short duration.

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药物

舍曲林