生物属性的新volumizing透明质酸填充:系统回顾。

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何鸿燊D,贾格迪奥J

生物属性的新volumizing透明质酸填充:系统回顾。

J药物北京医学。2015年1月,14 (1):50-4。

PubMed ID

25607908 (在PubMed

]

文摘

背景:透明质酸(HA)皮下注射是有效和安全的面部rhytides的校正。新的volumizing公顷填料,20毫克/毫升HA皮肤填充剂(Juvederm (R) Voluma (R),爱力根公司,欧文,CA),是唯一的HA填料的FDA表明面部volumization由于老年性面部体积损失。目的:评价生物属性,包括生物化学、生物物理和流变,这个新20毫克/毫升的HA真皮填充并讨论这些属性在临床应用的重要性。方法和材料:计算机的系统搜索书目数据库Medline、Embase, E必威国际appmbal,生命现象,SciSearch,帕斯卡,HCAPlus,异丙醇,论文摘要和关键术语“Voluma。”Four articles on the biological properties of this new 20 mg/ ml HA dermal filler were suitable for inclusion in this review. RESULTS: Biological analysis of elasticity and viscosity values of this new 20 mg/ml HA dermal filler demonstrated intermediate properties in three studies and high in one study compared to other HA dermal fillers. This 20 mg/ml HA dermal filler retained the highest elasticity and viscosity values at temperature of 37 degrees C. Histology demonstrated that this 20 mg/ml HA dermal filler has an intermediate pattern of distribution within the superficial and deep reticular dermis. CONCLUSION: This 20 mg/ml HA dermal filler demonstrated volumizing ability, and maintaining viscosity and free-flowing characteristics for easy injection, tissue lifting, and molding. We hope future research incorporates biological properties analysis of this HA dermal filler in clinical trials.

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药物

透明质酸