评估输尿管通畅post-indigo胭脂时代:一个随机对照试验。
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Grimes CL, Patankar年代,Ryntz T,菲利普·N·辛普森K, Truong M,年轻的C, Advincula, Madueke-Laveaux OS,沃尔特斯R, Ananth简历,金正日JH
评估输尿管通畅post-indigo胭脂时代:一个随机对照试验。
比较。Gynecol。2017年11月,217 (5):601. e1 - 601. - e10。doi: 10.1016 / j.ajog.2017.07.012。Epub 2017年7月18日。
- PubMed ID
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28729014 (在PubMed]
- 文摘
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背景:许多妇科、泌尿道的和骨盆重建手术需要精确的术中评估输尿管通畅。目的:我们进行了一个随机对照试验比较外科医生满意4的方法评估输尿管膀胱镜检查期间开放的良性妇科或骨盆重建手术:口服非那吡啶,静脉注射荧光素钠、甘露醇膀胱膨胀,生理盐水膀胱膨胀。研究设计:我们进行了一次选取随机对照试验的方法用来评估输尿管膀胱镜检查期间开放时良性妇科或骨盆重建手术。受试者被随机分配接受200毫克口服非那吡啶,25 mg静脉注射荧光素钠、甘露醇膀胱膨胀,或生理盐水冲洗膀胱膨胀在膀胱镜检查。主要结果是外科医生满意的方法,通过一个100毫米的视觉模拟量表评估0分代表强大的协议和100年代表强烈反对的声明。次要结果包括比较视觉模拟量表的反应对缓解输尿管喷流的每个方法和可视化,膀胱粘膜尿道,和有效的信息,包括时间的外科医生的信心输尿管飞机。不良事件评价手术后至少6周,并通过研究结束的。所有统计分析是基于intent-to-treat原则,2-tailed和比较。结果:在130年,受试者被随机分配到非那吡啶(n = 33),荧光素钠(n = 32)、甘露醇(n = 32),或生理盐水(n = 33)。在随机化,病人被类似的跨组特征。 With regard to the primary outcome, mannitol was the method that physicians found most satisfactory on a visual analog scale. The median (range) scores for physicians assessing ureteral patency were 48 (0-83), 20 (0-82), 0 (0-44), and 23 (3-96) mm for phenazopyridine, sodium fluorescein, mannitol, and normal saline, respectively (P < .001). Surgery length, cystoscopy length, and time to surgeon confidence in visualization of ureteral jets were not different across the 4 randomized groups. During the 189-day follow-up, no differences in adverse events were seen among the groups, including urinary tract infections. CONCLUSION: The use of mannitol during cystoscopy to assess ureteral patency provided surgeons with the most overall satisfaction, ease of use, and superior visualization without affecting surgery or cystoscopy times. There were no differences in adverse events, including incidence of urinary tract infections.
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