在羊Medetomidine-midazolam镇静。

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Raekallio M, Tulamo RM, Valtamo T

在羊Medetomidine-midazolam镇静。

《兽医Scand。1998; 39 (1): 127 - 34。

PubMed ID

9592953 (在PubMed

]

文摘

七只羊镇静3倍:medetomidine(15毫克公斤),与咪达唑仑(0.1毫克公斤),与药物的结合。静脉注射药物的管理。心跳和呼吸频率测量。动脉血液样本收集,PaO2 PaCO2, pH值、血红蛋白浓度和饱和度,基地多余的测定。收缩压和平均动脉压与medetomidine-midazolam记录之前和之后的治疗。咪达唑仑medetomidine引起的增加了休息的时间。经过政府的咪达唑仑,仅4 7只羊的镇静和其他3很兴奋。medetomidine和medetomidine-midazolam后心率降低。一只羊遭受心脏骤停medetomidine-midazolam注射后,它需要复苏。PaO2 medetomidine后血红蛋白氧饱和度降低,medetomidine-midazolam显著低氧血引起的。 PaCO2 increased after medetomidine, both alone and combined with midazolam, but arterial pH was within the reference values after all drug administrations. Systolic and mean arterial pressures decreased after medetomidine-midazolam. This study indicates that though in sheep midazolam potentiates the sedative effect of medetomidine, the combination of medetomidine and midazolam also reduces the in PaO2 and haemoglobin oxygen saturation more than medetomidine alone. The results indicate that a medetomidine-midazolam combination is unsafe for sheep at the doses studied.

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药物

Medetomidine