在马沙利霉素中毒。

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的话,Magdesian公斤,彼得森TS, Galey FD

在马沙利霉素中毒。

J是兽医协会。2007年6月15日,230 (12):1822 - 6。

PubMed ID

17571983 (在PubMed

]

文摘

案例描述:美国4漆小母马是评估,因为突然发作性共济失调发展到休息。五个额外的马从相同和邻近的前提了表现不佳的迹象,广义的弱点,共济失调,和休息;2的马也被评估。一批新的商业饲料添加剂已被介绍给马的前3天内饮食对每一个农场。临床发现:除了休息,发现身体和神经系统检查的不起眼的小马驹。另2匹马有广义的弱点和温和性共济失调,和1马也持续心动过速。小马驹了温和与嗜中性白细胞增多,高血糖,轻度高血清肌酸激酶活性。颈部放射学结果,CSF分析和评估重金属和硒浓度的血液和血清中维生素E浓度在参考范围内。饲料分析发现高浓度的离子载体抗菌盐霉素。治疗和结果:5影响马幸存下来,但是小马驹被安乐死。 At necropsy, a major histopathologic finding was severe vacuolation within neurons of the dorsal root ganglia, which was compatible with ionophore toxicosis. The surviving horses developed muscle atrophy, persistent weakness, and ataxia. CLINICAL RELEVANCE: In horses, ionophore toxicosis should be considered as a differential diagnosis for acute weakness, ataxia, recumbency, or sudden death. Furthermore, ionophore toxicosis should be considered as a cause of poor performance, weakness, muscle wasting, and cardiac arrhythmias in horses. Surviving horses may have impaired athletic performance.

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药物

盐霉素