Janus Kinases, antagonists & inhibitors

Name
Janus Kinases, antagonists & inhibitors
Accession Number
DBCAT001908
Description

Not Available

Drugs
Drug Drug Description
Ruxolitinib A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
Drugs & Drug Targets
Drug Target Type
Ruxolitinib Tyrosine-protein kinase JAK1 target
Ruxolitinib Tyrosine-protein kinase JAK2 target
Ruxolitinib Cytochrome P450 3A4 enzyme
Ruxolitinib Cytochrome P450 2C9 enzyme
Ruxolitinib Serum albumin carrier
Ruxolitinib Tyrosine-protein kinase JAK3 target
Ruxolitinib Non-receptor tyrosine-protein kinase TYK2 target