Janus Kinases, antagonists & inhibitors
- Name
- Janus Kinases, antagonists & inhibitors
- Accession Number
- DBCAT001908
- Description
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Not Available
- Drugs
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Drug Drug Description Ruxolitinib A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment. - Drugs & Drug Targets
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Drug Target Type Ruxolitinib Tyrosine-protein kinase JAK1 target Ruxolitinib Tyrosine-protein kinase JAK2 target Ruxolitinib Cytochrome P450 3A4 enzyme Ruxolitinib Cytochrome P450 2C9 enzyme Ruxolitinib Serum albumin carrier Ruxolitinib Tyrosine-protein kinase JAK3 target Ruxolitinib Non-receptor tyrosine-protein kinase TYK2 target