This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Gardasil 9
Generic Name
Human papillomavirus type 58 L1 capsid protein antigen
DrugBank Accession Number
DB10314
Background

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Type 58 which are produced by separate fermentations in recombinantSaccharomyces cerevisiaeand self-assembled into VLPs.

类型
Biotech
Groups
Approved
Biologic Classification
Vaccines
Other vaccines
Synonyms
  • L1 protein, Human papillomavirus type 58 Vaccine
  • Recombinant human papillomavirus type 58 L1 protein

Ph值armacology

Indication

Not Available

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Associated Conditions
Contraindications & Blackbox Warnings
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Ph值armacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Interactions

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Food Interactions
Not Available

Products

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Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 11 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 16 L1 capsid protein antigen(60 ug/0.5mL)+Human papillomavirus type 18 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 31 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 33 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 45 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 52 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 6 L1 capsid protein antigen(30 ug/0.5mL) Injection, suspension Intramuscular Merck Sharp & Dohme Llc 2014-12-10 Not applicable US flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-02-09 Not applicable EU flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 mcg / 0.5 mL)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg / 0.5 mL)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg / 0.5 mL)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg / 0.5 mL)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg / 0.5 mL)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg / 0.5 mL)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg / 0.5 mL)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg / 0.5 mL)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg / 0.5 mL) Suspension Intramuscular Merck Ltd. 2015-03-18 Not applicable Canada flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 11 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 16 L1 capsid protein antigen(60 ug/0.5mL)+Human papillomavirus type 18 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 31 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 33 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 45 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 52 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 6 L1 capsid protein antigen(30 ug/0.5mL) Injection, suspension Intramuscular A-S Medication Solutions 2014-12-10 Not applicable US flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 11 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 16 L1 capsid protein antigen(60 ug/0.5mL)+Human papillomavirus type 18 L1 capsid protein antigen(40 ug/0.5mL)+Human papillomavirus type 31 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 33 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 45 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 52 L1 capsid protein antigen(20 ug/0.5mL)+Human papillomavirus type 6 L1 capsid protein antigen(30 ug/0.5mL) Injection, suspension Intramuscular Merck Sharp & Dohme Llc 2014-12-10 Not applicable US flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-02-09 Not applicable EU flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-02-09 Not applicable EU flag
Gardasil 9 Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2020-12-18 Not applicable EU flag
GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, solution Intramuscular MERCK SHARP DOHME İLAÇLARI LTD. ŞTİ. 2020-08-14 Not applicable Turkey flag
GARDASIL 9 SUSPENSION FOR INJECTION Human papillomavirus type 58 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 11 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 16 L1 capsid protein antigen(60 mcg)+Human papillomavirus type 18 L1 capsid protein antigen(40 mcg)+Human papillomavirus type 31 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 33 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 45 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 52 L1 capsid protein antigen(20 mcg)+Human papillomavirus type 6 L1 capsid protein antigen(30 mcg) Injection, suspension Intramuscular MSD PHARMA (SINGAPORE) PTE. LTD. 2016-12-16 Not applicable

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
94Y15HP7LF
CAS number
Not Available

References

一般引用
Not Available
PubChem Substance
347910493
RxNav
1596934

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Ph值ase Status Purpose Conditions Count
4 Active Not Recruiting Prevention Allogeneic Hematopoietic Stem Cell Transplant Recipient/Hematopoietic and Lymphoid Cell Neoplasm 1
4 Active Not Recruiting Prevention Papillomavirus Infections 1
4 Active Not Recruiting Treatment High Grade Anal Canal Intraepithelial Neoplasia/High Grade Vulvar Squamous Intraepithelial Lesion 1
4 Completed Prevention Papilloma Viral Infection 1
4 Enrolling by Invitation Prevention Cervical Carcinoma/Human Papillomavirus (HPV) Infections 1
4 Enrolling by Invitation Prevention Human Papilloma Virus-Related Cervical Carcinoma/Human Papillomavirus (HPV) Infections 1
4 Not Yet Recruiting Prevention Anal Intraepithelial Neoplasia (AIN)/Cervical Intraepithelial Neoplasia (CIN)/Human Immunodeficiency Virus (HIV) Infections/Oral Cavity Infection/Papillomavirus Infections/Papillomavirus Vaccines/Serology 1
4 Recruiting Basic Science Human Papilloma Virus (HPV) 1
4 Recruiting Prevention Coronavirus Disease 2019 (COVID‑19)/Human Papillomavirus (HPV) Infections 1
4 Recruiting Prevention Human Immunodeficiency Virus (HIV) Infections 1

Ph值armacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Injection, suspension Intramuscular
Injection, suspension Intramuscular; Parenteral
Suspension Intramuscular
Injection, solution Intramuscular
Injection, suspension Intramuscular 40 mcg
Injection, suspension
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 01, 2015 20:03 / Updated at February 13, 2021 10:52