This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sodium feredetate
DrugBank Accession Number
DB13381
Background

Not Available

Type
Small Molecule
Groups
Approved
Structure
Weight
Average: 367.047
Monoisotopic: 366.984071
Chemical Formula
C10H12FeN2NaO8
Synonyms
  • Feredato de sodio
  • Ferédétate de sodium
  • Ferric sodium EDTA
  • Ferric sodium ethylenediaminetetraacetate
  • Ferrostrane
  • Ferrostrene
  • Monosodium ferric EDTA
  • Natrii feredetas
  • Sodium feredetate
  • Sodium ferric EDTA
  • Sodium iron EDTA
  • Sodium ironedetate

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction
Alendronic acid Sodium feredetate can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Almasilate Almasilate can cause a decrease in the absorption of Sodium feredetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium phosphate Aluminium phosphate can cause a decrease in the absorption of Sodium feredetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminum hydroxide Aluminum hydroxide can cause a decrease in the absorption of Sodium feredetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Asenapine Asenapine can cause a decrease in the absorption of Sodium feredetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Sodium feredetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Phosphate Sodium feredetate can cause a decrease in the absorption of Calcium Phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium phosphate dihydrate Sodium feredetate can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Carbidopa Sodium feredetate can cause a decrease in the absorption of Carbidopa resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cefdinir Sodium feredetate can cause a decrease in the absorption of Cefdinir resulting in a reduced serum concentration and potentially a decrease in efficacy.
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Food Interactions
  • Avoid milk and dairy products.
  • Avoid multivalent ions.
  • Limit caffeine intake. Food and beverages containing caffeine may reduce iron absorption.
  • Take separate from antacids.
  • Take with foods containing vitamin C. Foods rich in vitamin C increase the absorption of iron.

Products

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Active Moieties
Name Kind UNII CAS InChI Key
Iron unknown E1UOL152H7 7439-89-6 XEEYBQQBJWHFJM-UHFFFAOYSA-N
Ferric cation ionic 91O4LML611 20074-52-6 VTLYFUHAOXGGBS-UHFFFAOYSA-N
International/Other Brands
Calmosine/Sytron
Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
Bal-Care DHA Sodium feredetate(25.65 mg/1)+Ascorbic acid(120 mg/1)+Beta carotene(2850 iU / 1)+Calcium carbonate(219 mg/1)+Cholecalciferol(840 [iU]/1)+Cupric oxide(2 mg/1)+Cyanocobalamin(.012 mg/1)+DL-alpha tocopheryl acetate(3 mg/1)+Folic acid(1 mg/1)+Iodine(.223 mg/1)+Iron sucrose(1.35 mg/1)+氧化镁(25 mg/1)+Nicotinamide(20 mg/1)+Omega-3 fatty acids(430 mg/1)+Pyridoxine hydrochloride(50 mg/1)+Riboflavin(4 mg/1)+Thiamine mononitrate(1.8 mg/1)+Zinc oxide(25 mg/1) Kit Oral Pru Gen Pharmaceuticals 2012-05-01 Not applicable 我们flag
Bal-Care DHA Essential Sodium feredetate(25.65 mg/1)+Ascorbic acid(120 mg/1)+Beta carotene(2850 iU / 1)+Calcium carbonate(219 mg/1)+Cholecalciferol(840 [iU]/1)+Cupric oxide(2 mg/1)+Cyanocobalamin(.012 mg/1)+DL-alpha tocopheryl acetate(3 mg/1)+Folic acid(1 mg/1)+Iodine(.223 mg/1)+Iron sucrose(1.35 mg/1)+氧化镁(25 mg/1)+Nicotinamide(20 mg/1)+Omega-3 fatty acids(374 mg/1)+Pyridoxine hydrochloride(50 mg/1)+Riboflavin(4 mg/1)+Thiamine mononitrate(1.8 mg/1)+Zinc oxide(25 mg/1) Kit Oral Pru Gen Pharmaceuticals 2012-05-01 Not applicable 我们flag
Cavan-EC SOD DHA Sodium feredetate(30 mg/1)+Ascorbic acid(130 mg/1)+Beta carotene(3000 [iU]/1)+Calcium(230 mg/1)+Cholecalciferol(410 [iU]/1)+Copper(2 mg/1)+Cyanocobalamin(12 ug/1)+Folic acid(1 mg/1)+(25 mg/1)+Nicotinamide(20 mg/1)+Omega-3 fatty acids(440 mg/1)+Pyridoxine hydrochloride(28 mg/1)+Riboflavin(4 mg/1)+Thiamine mononitrate(1.8 mg/1)+Vitamin E(30 mg/1)+Zinc(26 mg/1) Kit Oral Seton Pharmaceuticals 2010-01-10 2014-07-15 我们flag
Cavan-EC SOD DHA Sodium feredetate(30 mg/1)+Ascorbic acid(130 mg/1)+Beta carotene(3000 [iU]/1)+Calcium carbonate(230 mg/1)+Cholecalciferol(410 [iU]/1)+Cyanocobalamin(12 ug/1)+DL-alpha tocopheryl acetate(30 mg/1)+Folic acid(1 mg/1)+氧化镁(25 mg/1)+Nicotinamide(20 mg/1)+Omega-3 fatty acids(440 mg/1)+Pyridoxine hydrochloride(28 mg/1)+Riboflavin(4 mg/1)+Zinc oxide(26 mg/1) Kit Oral Physicians Total Care, Inc. 2010-08-24 2013-01-15 我们flag

Categories

ATC Codes
B03AB03 — Sodium feredetate
Drug Categories
Chemical TaxonomyProvided byClassyfire
Description
This compound belongs to the class of organic compounds known as tetracarboxylic acids and derivatives. These are carboxylic acids containing exactly four carboxyl groups.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Tetracarboxylic acids and derivatives
Direct Parent
Tetracarboxylic acids and derivatives
Alternative Parents
Alpha amino acids/Trialkylamines/Carboxylic acid salts/Amino acids/Organic transition metal salts/Carboxylic acids/Organopnictogen compounds/Organic zwitterions/Organic sodium salts/Organic oxides
show 2 more
Substituents
Aliphatic acyclic compound/Alpha-amino acid/Alpha-amino acid or derivatives/Amine/Amino acid/Amino acid or derivatives/Carbonyl group/Carboxylic acid/Carboxylic acid salt/Hydrocarbon derivative
show 14 more
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
organic sodium salt, iron chelate (CHEBI:78292)
Affected organisms
Not Available

Chemical Identifiers

UNII
403J23EMFA
CAS number
15708-41-5
InChI Key
MKWYFZFMAMBPQK-UHFFFAOYSA-J
InChI
InChI=1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4
IUPAC Name
sodium 5-(carboxymethyl)-3,10,13-trioxo-2,11,12-trioxa-5,8lambda5-diaza-1-ferratetracyclo[6.3.3.0^{1,5}.0^{1,8}]tetradecan-5-ium-8-ylium-1,1-diuide
SMILES
[Na+].[O-]C(=O)C[N+]12CC[N+]34CC(=O)O[Fe--]13(OC(=O)C2)OC(=O)C4

References

一般引用
Not Available
KEGG Drug
D07145
ChemSpider
25555
RxNav
105673
ChEBI
78292
ChEMBL
CHEMBL1705709

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Not Available Recruiting Treatment Craniosynostosis 1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Kit Oral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 0.0541 mg/mL ALOGPS
logP 1.45 ALOGPS
logP -1.5 Chemaxon
logS -3.9 ALOGPS
pKa (Strongest Acidic) 1.12 Chemaxon
pKa (Strongest Basic) -7 Chemaxon
Physiological Charge -1 Chemaxon
Hydrogen Acceptor Count 5 Chemaxon
Hydrogen Donor Count 0 Chemaxon
Polar Surface Area 119.03 Å2 Chemaxon
Rotatable Bond Count 2 Chemaxon
Refractivity 71.6 m3·mol-1 Chemaxon
Polarizability 26.41 Å3 Chemaxon
Number of Rings 4 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter No Chemaxon
Veber's Rule No Chemaxon
MDDR-like规则 No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Spectrum Spectrum Type Splash Key
Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available

Drug created at June 23, 2017 20:40 / Updated at February 21, 2021 18:54