Ascites

Drug Drug Name Drug Description
DB00594 Amiloride A pyrizine compound used to treat hypertension and congestive heart failure.
DB00903 Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
DB00695 Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DB00999 Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB00421 Spironolactone An aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia.
Drug Drug Name Target Type
DB00594 Amiloride Amiloride-sensitive sodium channel subunit beta target
DB00594 Amiloride Acid-sensing ion channel 1 target
DB00594 Amiloride Amiloride-sensitive amine oxidase [copper-containing] target
DB00594 Amiloride Amiloride-sensitive sodium channel subunit alpha target
DB00594 Amiloride Amiloride-sensitive sodium channel subunit gamma target
DB00594 Amiloride Sodium/hydrogen exchanger 1 target
DB00594 Amiloride Acid-sensing ion channel 2 target
DB00594 Amiloride Amiloride-sensitive sodium channel subunit delta target
DB00594 Amiloride Urokinase-type plasminogen activator target
DB00594 Amiloride 溶质载体家庭22个成员2 transporter
DB00594 Amiloride Solute carrier family 22 member 4 transporter
DB00594 Amiloride Amiloride-sensitive amine oxidase [copper-containing] enzyme
DB00594 Amiloride Amiloride-sensitive amine oxidase [copper-containing] enzyme
DB00903 Etacrynic acid Solute carrier family 12 member 1 target
DB00903 Etacrynic acid Sodium/potassium-transporting ATPase subunit alpha-1 target
DB00903 Etacrynic acid Glutathione S-transferase A2 enzyme
DB00903 Etacrynic acid Serum albumin carrier
DB00903 Etacrynic acid Solute carrier family 22 member 6 transporter
DB00903 Etacrynic acid Lymphoid enhancer-binding factor 1 target
DB00903 Etacrynic acid Glutathione S-transferase P target
DB00695 Furosemide Solute carrier family 12 member 1 target
DB00695 Furosemide Serum albumin carrier
DB00695 Furosemide Solute carrier family 22 member 6 transporter
DB00695 Furosemide Solute carrier family 22 member 5 transporter
DB00695 Furosemide Solute carrier family 22 member 8 transporter
DB00695 Furosemide Canalicular multispecific organic anion transporter 1 transporter
DB00695 Furosemide Solute carrier organic anion transporter family member 2A1 transporter
DB00695 Furosemide Solute carrier family 22 member 11 transporter
DB00695 Furosemide 6-phosphogluconate dehydrogenase, decarboxylating enzyme
DB00695 Furosemide Carbonic anhydrase 2 target
DB00695 Furosemide UDP-glucuronosyltransferase 1-1 enzyme
DB00695 Furosemide Thyroxine-binding globulin carrier
DB00695 Furosemide G-protein coupled receptor 35 target
DB00999 Hydrochlorothiazide Solute carrier family 12 member 3 target
DB00999 Hydrochlorothiazide Solute carrier family 22 member 6 transporter
DB00999 Hydrochlorothiazide Calcium-activated potassium channel subunit alpha-1 target
DB00999 Hydrochlorothiazide Serum albumin carrier
DB00999 Hydrochlorothiazide Solute carrier family 22 member 11 transporter
DB00999 Hydrochlorothiazide Multidrug resistance-associated protein 4 transporter
DB00999 Hydrochlorothiazide Solute carrier family 22 member 8 transporter
DB00421 Spironolactone Mineralocorticoid receptor target
DB00421 Spironolactone 阶段chrome P450 2C8 enzyme
DB00421 Spironolactone Canalicular multispecific organic anion transporter 1 transporter
DB00421 Spironolactone P-glycoprotein 1 transporter
DB00421 Spironolactone Solute carrier organic anion transporter family member 1A2 transporter
DB00421 Spironolactone 阶段chrome P450 11B1, mitochondrial enzyme
DB00421 Spironolactone Androgen receptor target
DB00421 Spironolactone Progesterone receptor target
DB00421 Spironolactone Glucocorticoid receptor target
DB00421 Spironolactone 阶段chrome P450 11B2, mitochondrial target
DB00421 Spironolactone Steroid 17-alpha-hydroxylase/17,20 lyase target
DB00421 Spironolactone 3-oxo-5-alpha-steroid 4-dehydrogenase target
DB00421 Spironolactone Sex hormone-binding globulin target
DB00421 Spironolactone Voltage-dependent calcium channel target
DB00421 Spironolactone Nuclear receptor subfamily 1 group I member 2 target
DB00421 Spironolactone Bile salt export pump transporter
DB00421 Spironolactone Serum albumin carrier
DB00421 Spironolactone alpha1-acid glycoprotein carrier
Drug Drug Name Phase Status Count
DB00062 Albumin human 1 Completed 2
DB09038 Empagliflozin 1 Active Not Recruiting 1
DB09153 Sodium chloride 1 Completed 1
DB06212 Tolvaptan 1 Completed 1
DB06403 Ambrisentan 2 Terminated 1
DB14825 Danvatirsen 2 Terminated 1
DB00700 Eplerenone 2 Withdrawn 1
DB00695 Furosemide 2 Completed 1
DB00104 Octreotide 2 Completed 1
DB14923 Satavaptan 2 Completed 3
DB01015 Sulfamethoxazole 2 Terminated 1
DB01268 Sunitinib 2 Terminated 1
DB02638 Terlipressin 2 Active Not Recruiting 1
DB06212 Tolvaptan 2 Completed 1
DB00440 Trimethoprim 2 Terminated 1
DB08885 Aflibercept 2 / 3 Completed 1
DB00437 Allopurinol 2 / 3 Recruiting 1
DB01076 Atorvastatin 2 / 3 Recruiting 1
DB00438 Ceftazidime 2 / 3 Terminated 1
DB00080 Daptomycin 2 / 3 Terminated 1
DB00760 Meropenem 2 / 3 Terminated 1
DB00641 Simvastatin 2 / 3 Recruiting 1
DB02638 Terlipressin 2 / 3 Completed 1
DB01059 Norfloxacin 3 Recruiting 1
DB00571 Propranolol 3 Unknown Status 1
DB01220 Rifaximin 3 Active Not Recruiting 1
DB01220 Rifaximin 3 Recruiting 1
DB14923 Satavaptan 3 Completed 1
DB14923 Satavaptan 3 Terminated 2
DB06212 Tolvaptan 3 Completed 1
DB00062 Albumin human 4 Completed 3
DB09393 Amino acids 4 Unknown Status 1
DB01136 Carvedilol 4 Completed 1
DB00537 Ciprofloxacin 4 Withdrawn 1
DB00695 Furosemide 4 Completed 2
DB00678 Losartan 4 Unknown Status 1
DB00211 Midodrine 4 Completed 1
DB00104 Octreotide 4 Completed 1
DB01132 Pioglitazone 4 Completed 1
DB00571 Propranolol 4 Completed 1
DB01220 Rifaximin 4 Completed 1
DB00421 Spironolactone 4 Completed 1
DB06212 Tolvaptan 4 Completed 1
DB06212 Tolvaptan 4 Unknown Status 1
DB00062 Albumin human Not Available Completed 1
DB00062 Albumin human Not Available Suspended 1
DB00062 Albumin human Not Available Unknown Status 1
DB00211 Midodrine Not Available Withdrawn 1