真性红细胞增多(PV)

Also known as:真性红细胞增多/Polycythaemia vera/Polycytemia Vera/[M]Polycythemia vera (morphologic abnormality)/Primary polycythaemia/Vaquez's disease/Erythremia (morphologic abnormality)/Primary polycythemia/Polycythemia rubra vera/Polycythaemia rubra vera/Polycythemia vera (disorder)/Polycythemia vera (morphologic abnormality)/Polycythemia vera -RETIRED-/(Solitary myeloma) or (polycythaemia [rubra] vera) or (other uncertain neoplasms NOS)

Drug Drug Name Drug Description
DB00945 Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB01008 Busulfan An alkylating agent used to treat chronic myelogenous leukemia.
DB01005 Hydroxyurea An antimetabolite used to treat sickle cell anemia crisis.
DB00888 Mechlorethamine An antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
DB11697 Pacritinib A kinase inhibitor used for the treatment of primary and secondary myelofibrosis in adult patients with significantly reduced platelet counts.
DB15119 Ropeginterferon alfa-2b A mono-pegylated type I interferon used to treat polycythemia vera.
Drug Drug Name Target Type
DB00945 Acetylsalicylic acid Prostaglandin G/H synthase 1 target
DB00945 Acetylsalicylic acid Prostaglandin G/H synthase 2 target
DB00945 Acetylsalicylic acid Aldo-keto reductase family 1 member C1 target
DB00945 Acetylsalicylic acid 溶解te carrier family 22 member 6 transporter
DB00945 Acetylsalicylic acid P-glycoprotein 1 transporter
DB00945 Acetylsalicylic acid 细胞色素P450 2C19 enzyme
DB00945 Acetylsalicylic acid 细胞色素P450 2C9 enzyme
DB00945 Acetylsalicylic acid 5'-AMP-activated protein kinase target
DB00945 Acetylsalicylic acid Endothelin-1 receptor target
DB00945 Acetylsalicylic acid Cellular tumor antigen p53 target
DB00945 Acetylsalicylic acid 78 kDa glucose-regulated protein target
DB00945 Acetylsalicylic acid Ribosomal protein S6 kinase alpha-3 target
DB00945 Acetylsalicylic acid NF-kappa-B inhibitor alpha target
DB00945 Acetylsalicylic acid Tumor necrosis factor-inducible gene 6 protein target
DB00945 Acetylsalicylic acid Caspase-1 target
DB00945 Acetylsalicylic acid Caspase-3 target
DB00945 Acetylsalicylic acid Inhibitor of nuclear factor kappa-B kinase subunit beta target
DB00945 Acetylsalicylic acid Extracellular signal-regulated kinase (ERK) target
DB00945 Acetylsalicylic acid G1/S-specific cyclin-D1 target
DB00945 Acetylsalicylic acid Myc proto-oncogene protein target
DB00945 Acetylsalicylic acid Proliferating cell nuclear antigen target
DB00945 Acetylsalicylic acid Cyclin A target
DB00945 Acetylsalicylic acid UDP-glucuronosyltransferase 1-6 enzyme
DB00945 Acetylsalicylic acid Arylamine N-acetyltransferase 2 enzyme
DB00945 Acetylsalicylic acid 溶解te carrier family 22 member 8 transporter
DB00945 Acetylsalicylic acid Sialidase-1 target
DB01008 Busulfan DNA target
DB01008 Busulfan 细胞色素P450 3A4 enzyme
DB01008 Busulfan Glutathione S-transferase A2 enzyme
DB01008 Busulfan Glutathione S-transferase A1 enzyme
DB01008 Busulfan Glutathione S-transferase Mu 1 enzyme
DB01008 Busulfan Glutathione S-transferase P enzyme
DB01008 Busulfan Microsomal glutathione S-transferase 2 enzyme
DB01005 Hydroxyurea Ribonucleoside-diphosphate reductase large subunit target
DB01005 Hydroxyurea 细胞色素P450 2D6 enzyme
DB00888 Mechlorethamine DNA target
DB00888 Mechlorethamine Cholinesterase enzyme
DB11697 Pacritinib 细胞色素P450 3A4 enzyme
DB11697 Pacritinib 细胞色素P450 1A2 enzyme
DB11697 Pacritinib Tyrosine-protein kinase JAK2 target
DB11697 Pacritinib Receptor-type tyrosine-protein kinase FLT3 target
DB11697 Pacritinib P-glycoprotein 1 transporter
DB11697 Pacritinib ATP-binding cassette sub-family G member 2 transporter
DB11697 Pacritinib 溶质载体家庭22个成员1 transporter
DB11697 Pacritinib 细胞色素P450 2C19 enzyme
DB11697 Pacritinib 溶解te carrier family 22 member 2 transporter
DB15119 Ropeginterferon alfa-2b 细胞色素P450 1A2 enzyme
DB15119 Ropeginterferon alfa-2b 细胞色素P450 2D6 enzyme
DB15119 Ropeginterferon alfa-2b 细胞色素P450 2A6 enzyme
DB15119 Ropeginterferon alfa-2b Interferon alpha/beta receptor (IFNAR) target
Drug Drug Name Phase Status Count
DB09036 Siltuximab 0 Withdrawn 1
DB01169 Arsenic trioxide 1 Terminated 1
DB00928 Azacitidine 1 Completed 1
DB00958 Carboplatin 1 Active Not Recruiting 1
DB00987 Cytarabine 1 Completed 1
DB01262 Decitabine 1 Completed 1
DB00773 Etoposide 1 Completed 1
DB13040 Gandotinib 1 Completed 2
DB12645 Givinostat 1 Completed 1
DB12325 Idasanutlin 1 Completed 1
DB00619 Imatinib 1 Completed 1
DB00218 Moxifloxacin 1 Completed 1
DB00008 Peginterferon alfa-2a 1 Completed 1
DB08877 Ruxolitinib 1 Active Not Recruiting 1
DB09143 Sonidegib 1 Completed 1
DB01268 Sunitinib 1 Completed 1
DB01030 Topotecan 1 Active Not Recruiting 1
DB14989 Umbralisib 1 Active Not Recruiting 1
DB07232 Veliparib 1 Active Not Recruiting 1
DB02546 Vorinostat 1 Completed 1
DB05243 XL019 1 Terminated 2
DB06151 Acetylcysteine 1 / 2 Active Not Recruiting 1
DB00041 Aldesleukin 1 / 2 Completed 1
DB00928 Azacitidine 1 / 2 Active Not Recruiting 1
DB11105 Benzalkonium 1 / 2 Completed 1
DB00987 Cytarabine 1 / 2 Recruiting 1
DB00694 Daunorubicin 1 / 2 Recruiting 1
DB12645 Givinostat 1 / 2 Completed 1
DB06469 Lestaurtinib 1 / 2 Unknown Status 1
DB11697 Pacritinib 1 / 2 Completed 1
DB11759 Pevonedistat 1 / 2 Active Not Recruiting 1
DB08877 Ruxolitinib 1 / 2 Completed 2
DB08877 Ruxolitinib 1 / 2 Recruiting 1
DB09143 Sonidegib 1 / 2 Completed 1
DB17459 Therapeutic allogeneic lymphocytes 1 / 2 Completed 1
DB11581 Venetoclax 1 / 2 Active Not Recruiting 1
DB01955 1,4-Butanediol 2 Completed 1
DB00945 Acetylsalicylic acid 2 Active Not Recruiting 1
DB00945 Acetylsalicylic acid 2 Completed 1
DB00945 Acetylsalicylic acid 2 Recruiting 1
DB00945 Acetylsalicylic acid 2 Withdrawn 1
DB06605 Apixaban 2 Recruiting 1
DB17234 Bomedemstat 2 Recruiting 2
DB01008 Busulfan 2 Completed 2
DB00958 Carboplatin 2 Active Not Recruiting 1
DB00758 Clopidogrel 2 Withdrawn 1
DB00531 Cyclophosphamide 2 Active Not Recruiting 1
DB00531 Cyclophosphamide 2 Completed 3
DB00531 Cyclophosphamide 2 Recruiting 1
DB00091 Cyclosporine 2 Completed 1
DB01254 Dasatinib 2 Completed 1
DB01254 Dasatinib 2 Terminated 1
DB01262 Decitabine 2 Recruiting 1
DB00530 Erlotinib 2 Terminated 1
DB12500 Fedratinib 2 Recruiting 1
DB01073 Fludarabine 2 Active Not Recruiting 1
DB01073 Fludarabine 2 Completed 7
DB01073 Fludarabine 2 Recruiting 1
DB12645 Givinostat 2 Completed 1
DB01005 Hydroxyurea 2 Completed 1
DB15126 IMG-7289 2 Recruiting 2
DB12325 Idasanutlin 2 Terminated 1
DB00619 Imatinib 2 Completed 3
DB14909 Imetelstat 2 Completed 1
DB05258 Interferon alfa 2 Completed 1
DB12154 Itacitinib 2 Active Not Recruiting 1
DB12154 Itacitinib 2 Recruiting 1
DB00480 Lenalidomide 2 Completed 1
DB06469 Lestaurtinib 2 Completed 1
DB01042 Melphalan 2 Completed 1
DB01042 Melphalan 2 Recruiting 1
DB00563 Methotrexate 2 Completed 1
DB08893 Mirabegron 2 Completed 1
DB11763 Momelotinib 2 Completed 1
DB11763 Momelotinib 2 Terminated 1
DB00688 Mycophenolate mofetil 2 Completed 6
DB00688 Mycophenolate mofetil 2 Recruiting 1
DB15299 Navtemadlin 2 Unknown Status 1
DB14852 PRM-151 2 Completed 1
DB09037 Pembrolizumab 2 Completed 1
DB08910 Pomalidomide 2 Completed 1
DB00635 Prednisone 2 Completed 2
DB00172 Proline 2 Active Not Recruiting 1
DB15119 Ropeginterferon alfa-2b 2 Active Not Recruiting 2
DB15119 Ropeginterferon alfa-2b 2 Completed 1
DB08877 Ruxolitinib 2 Active Not Recruiting 1
DB08877 Ruxolitinib 2 Completed 1
DB08877 Ruxolitinib 2 Recruiting 2
DB08877 Ruxolitinib 2 Unknown Status 1
DB00864 Tacrolimus 2 Completed 5
DB00864 Tacrolimus 2 Recruiting 1
DB17459 Therapeutic allogeneic lymphocytes 2 Completed 1
DB04960 Tipifarnib 2 Completed 1
DB01030 Topotecan 2 Active Not Recruiting 1
DB11940 Triapine 2 Completed 1
DB07232 Veliparib 2 Active Not Recruiting 1
DB02546 Vorinostat 2 Unknown Status 1
DB00945 Acetylsalicylic acid 3 Recruiting 1
DB11105 Benzalkonium 3 Completed 1
DB11105 Benzalkonium 3 Recruiting 1
DB01005 Hydroxyurea 3 Completed 3
DB01005 Hydroxyurea 3 Recruiting 1
DB01005 Hydroxyurea 3 Terminated 1
DB05258 Interferon alfa 3 Completed 3
DB05258 Interferon alfa 3 Recruiting 1
DB00008 Peginterferon alfa-2a 3 Completed 1
DB00022 Peginterferon alfa-2b 3 Completed 1
DB00172 Proline 3 Completed 2
DB15119 Ropeginterferon alfa-2b 3 Completed 3
DB15119 Ropeginterferon alfa-2b 3 Recruiting 1
DB08877 Ruxolitinib 3 Completed 4
DB08877 Ruxolitinib 3 Recruiting 1
DB06603 Panobinostat 4 Recruiting 1
DB08877 Ruxolitinib 4 Recruiting 1
DB00098 Antithymocyte immunoglobulin (rabbit) Not Available Completed 1
DB01008 Busulfan Not Available Completed 2
DB00531 Cyclophosphamide Not Available Completed 1
DB00091 Cyclosporine Not Available Completed 1
DB01073 Fludarabine Not Available Completed 2
DB00529 Foscarnet Not Available Completed 1
DB01004 Ganciclovir Not Available Completed 1
DB00619 Imatinib Not Available Completed 1
DB01042 Melphalan Not Available Completed 1
DB00563 Methotrexate Not Available Completed 1
DB00688 Mycophenolate mofetil Not Available Completed 1
DB08877 Ruxolitinib Not Available Available 1
DB08877 Ruxolitinib Not Available Not Yet Recruiting 1
DB00864 Tacrolimus Not Available Completed 1
DB01610 Valganciclovir Not Available Completed 1