Holo-[acyl-carrier-protein] synthase

Details

Name
Holo-[acyl-carrier-protein] synthase
Synonyms
  • 2.7.8.7
  • 4'-phosphopantetheinyl transferase AcpS
  • Holo-ACP synthase
通用电气ne Name
acpS
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Amino acid sequence
>lcl|BSEQ0011824|Holo-[acyl-carrier-protein] synthase MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAF SKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSISHTDQFVTASVILEENHES
Number of residues
120
分子量
13388.005
Theoretical pI
6.1
GO Classification
Functions
holo-[acyl-carrier-protein] synthase activity/magnesium ion binding
Processes
fatty acid biosynthetic process
Components
cytoplasm
通用电气neral Function
Magnesium ion binding
Specific Function
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
通用电气ne sequence
>lcl|BSEQ0011825|Holo-[acyl-carrier-protein] synthase (acpS) ATGATAGTTGGACACGGAATTGACATCGAAGAATTGGCTTCGATAGAAAGCGCAGTTACA CGACATGAAGGATTTGCTAAGCGTGTACTGACCGCTCAGGAAATGGAGCGCTTCACCAGT CTCAAAGGACGCAGGCAAATAGAATATTTAGCTGGTCGCTGGTCGGCTAAGGAGGCCTTT TCCAAGGCTATGGGAACGGGCATTAGCAAGCTCGGTTTTCAGGATTTGGAAGTCTTGAAC AATGAACGTGGGGCGCCTTATTTTAGTCAGGCACCATTTTCAGGAAAGATTTGGCTGTCT ATCAGCCACACCGATCAGTTTGTGACAGCCAGTGTCATTTTGGAGGAAAATCATGAAAGC TAG
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
Resource Link
UniProtKB ID P0A2W7
UniProtKB Entry Name ACPS_STRR6
通用电气nBank Gene ID AF276617
通用电气neral References
  1. McAllister KA, Peery RB, Meier TI, Fischl AS, Zhao G: Biochemical and molecular analyses of the Streptococcus pneumoniae acyl carrier protein synthase, an enzyme essential for fatty acid biosynthesis. J Biol Chem. 2000 Oct 6;275(40):30864-72. [Article]
  2. Hoskins J, Alborn WE Jr, Arnold J, Blaszczak LC, Burgett S, DeHoff BS, Estrem ST, Fritz L, Fu DJ, Fuller W, Geringer C, Gilmour R, Glass JS, Khoja H, Kraft AR, Lagace RE, LeBlanc DJ, Lee LN, Lefkowitz EJ, Lu J, Matsushima P, McAhren SM, McHenney M, McLeaster K, Mundy CW, Nicas TI, Norris FH, O'Gara M, Peery RB, Robertson GT, Rockey P, Sun PM, Winkler ME, Yang Y, Young-Bellido M, Zhao G, Zook CA, Baltz RH, Jaskunas SR, Rosteck PR Jr, Skatrud PL, Glass JI: Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol. 2001 Oct;183(19):5709-17. [Article]

Drug Relations

Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details
DB01812 Adenosine 3',5'-diphosphate experimental unknown Details