Ferredoxin--NADP reductase

Details

Name
Ferredoxin--NADP reductase
Synonyms
  • 1.18.1.2
  • FNR
Gene Name
petH
Organism
Nostoc sp. (strain ATCC 29151 / PCC 7119)
Amino acid sequence
>lcl|BSEQ0012082|Ferredoxin--NADP reductase MSNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQ RITRLGGKIVTIQTVSALQQLNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKAFAK PPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHI KFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLE YKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMR TYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAIS REQKNPQGGRMYIQDRVAEHADELWQLIKNQKTHTYICGLRGMEEGIDAALSAAAAKEGV TWSDYQKDLKKAGRWHVETY
Number of residues
440
分子量
48865.145
Theoretical pI
8.37
GO Classification
Functions
ferredoxin-NADP+ reductase activity/flavin adenine dinucleotide binding/NADP binding
Processes
oxidation-reduction process
Components
phycobilisome
General Function
Nadp binding
Specific Function
Not Available
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
t细胞hylakoid membrane
Gene sequence
>拼箱| BSEQ0005788 ATGTCTAATCAAGGTGCTTTTGATG | 1323个基点GTGCTGCCAACGTAGAATCAGGTAGCCGCGTCTTC GTTTACGAAGTGGTGGGTATGCGTCAGAACGAAGAAACTGATCAAACGAACTACCCAATT CGTAAAAGTGGCAGTGTGTTCATTAGAGTGCCTTACAACCGCATGAATCAAGAAATGCAG CGTATCACTCGACTAGGCGGCAAGATTGTTACGATTCAAACAGTAAGCGCACTACAACAA CTCAATGGTAGAACTACCATTGCAACAGTAACAGATGCGTCTAGTGAGATTGCTAAGTCT GAGGGGAATGGTAAAGCCACACCTGTAAAAACTGATAGTGGAGCTAAAGCGTTCGCTAAA CCACCAGCTGAAGAACAGCTTAAGAAAAAAGACAACAAAGGCAACACCATGACTCAAGCG AAAGCCAAACACGCTGATGTTCCTGTTAATCTTTACCGTCCCAATGCTCCATTTATTGGT AAGGTAATCTCTAATGAACCACTGGTAAAAGAAGGCGGGATAGGTATTGTTCAGCACATT AAATTTGATCTAACTGGTGGTAACTTAAAGTACATCGAAGGTCAAAGTATTGGTATCATT CCACCAGGAGTGGACAAGAACGGCAAGCCGGAAAAATTGAGACTCTACTCCATTGCCTCG ACCCGTCACGGCGATGATGTGGATGATAAAACCATCTCACTGTGCGTCCGTCAATTAGAG TACAAACATCCAGAAAGCGGCGAAACAGTTTACGGTGTTTGTTCTACTTACTTGACTCAC ATTGAACCAGGTTCAGAAGTGAAAATCACTGGGCCTGTGGGTAAAGAAATGCTGTTACCC GATGATCCTGAAGCTAATGTCATCATGTTGGCAACAGGTACTGGTATTGCGCCTATGCGG ACTTACCTGTGGCGGATGTTCAAGGATGCAGAAAGAGCTGCTAACCCAGAATATCAATTC AAAGGATTCTCTTGGTTAGTCTTTGGTGTTCCTACAACTCCTAACATTCTTTATAAAGAA GAACTGGAAGAAATCCAACAAAAATATCCCGATAACTTCCGCCTAACTTACGCTATCAGC CGGGAGCAAAAGAATCCCCAAGGTGGCAGAATGTACATCCAAGACCGTGTGGCAGAACAC GCTGATGAACTGTGGCAATTAATCAAGAATCAAAAAACCCACACCTACATCTGTGGTTTG CGCGGTATGGAAGAGGGCATTGATGCTGCTTTAAGTGCTGCGGCTGCGAAAGAAGGTGTT ACCTGGAGTGATTACCAAAAAGACCTCAAGAAAGCTGGTCGCTGGCACGTAGAAACATAC TAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
Resource Link
UniProtKB ID P21890
UniProtKB Entry Name FENR_NOSSO
GenBank Gene ID X72394
General References
  1. Fillat MF, Flores E, Gomez-Moreno C: Homology of the N-terminal domain of the petH gene product from Anabaena sp. PCC 7119 to the CpcD phycobilisome linker polypeptide. Plant Mol Biol. 1993 Jul;22(4):725-9. [Article]
  2. Fillat MF, Bakker HA, Weisbeek PJ: Sequence of the ferredoxin-NADP(+)-reductase gene from Anabaena PCC 7119. Nucleic Acids Res. 1990 Dec 11;18(23):7161. [Article]
  3. Sancho J, Peleato ML, Gomez-Moreno C, Edmondson DE: Purification and properties of ferredoxin-NADP+ oxidoreductase from the nitrogen-fixing cyanobacteria Anabaena variabilis. Arch Biochem Biophys. 1988 Jan;260(1):200-7. [Article]
  4. Serre L, Vellieux FM, Medina M, Gomez-Moreno C, Fontecilla-Camps JC, Frey M: X-ray structure of the ferredoxin:NADP+ reductase from the cyanobacterium Anabaena PCC 7119 at 1.8 A resolution, and crystallographic studies of NADP+ binding at 2.25 A resolution. J Mol Biol. 1996 Oct 18;263(1):20-39. [Article]
  5. Martinez-Julvez M, Hermoso J, Hurley JK, Mayoral T, Sanz-Aparicio J, Tollin G, Gomez-Moreno C, Medina M: Role of Arg100 and Arg264 from Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal NADP+ binding and electron transfer. Biochemistry. 1998 Dec 22;37(51):17680-91. [Article]
  6. Mayoral T, Medina M, Sanz-Aparicio J, Gomez-Moreno C, Hermoso JA: Structural basis of the catalytic role of Glu301 in Anabaena PCC 7119 ferredoxin-NADP+ reductase revealed by x-ray crystallography. Proteins. 2000 Jan 1;38(1):60-9. [Article]
  7. Morales R, Kachalova G, Vellieux F, Charon MH, Frey M: Crystallographic studies of the interaction between the ferredoxin-NADP+ reductase and ferredoxin from the cyanobacterium Anabaena: looking for the elusive ferredoxin molecule. Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1408-12. [Article]

Drug Relations

Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details
DB03147 Flavin adenine dinucleotide approved unknown Details
DB03461 Nicotinamide adenine dinucleotide phosphate experimental unknown Details