D-hydantoinase

Details

Name
D-hydantoinase
Synonyms
  • 3.5.2.-
通用电气ne Name
hyuA
Organism
Ralstonia pickettii
Amino acid sequence
>lcl|BSEQ0016541|D-hydantoinase MDIIIKNGTIVTADGISRADLGIKDGKITQIGGALGPAERTIDAAGRYVFPGGIDVHTHV ETVSFNTQSADTFATATVAAACGGTTTIVDFCQQDRGHSLAEAVAKWDGMAGGKSAIDYG YHIIVLDPTDSVIEELEVLPDLGITSFKVFMAYRGMNMIDDVTLLKTLDKAVKTGSLVMV HAENGDAADYLRDKFVAEGKTAPIYHALSRPPRVEAEATARALALAEIVNAPIYIVHVTC EESLEEVMRAKSRGVRALAETCTHYLYLTKEDLERPDFEGAKYVFTPPARAKKDHDVLWN ALRNGVFETVSSDHCSWLFKGHKDRGRNDFRAIPNGAPGVEERLMMVYQGVNEGRISLTQ FVELVATRPAKVFGMFPQKGTIAVGSDADIVLWDPEAEMVIEQTAMHNAMDYSSYEGHKV KGVPKTVLLRGKVIVDEGSYVGEPTDGKFLKRRKYKQ
Number of residues
457
分子量
49931.52
Theoretical pI
5.93
GO Classification
Functions
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds/metal ion binding
Components
cytoplasm
通用电气neral Function
Metal ion binding
Specific Function
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasmic
通用电气ne sequence
>lcl|BSEQ0003420|1374 bp ATGGACATCATTATCAAAAACGGAACCATCGTGACCGCGGATGGCATTTCTCGCGCCGAT CTCGGGATCAAGGATGGCAAGATCACCCAGATCGGCGGCGCGCTCGGCCCAGCGGAGCGG ACGATCGACGCGGCCGGCCGCTACGTCTTTCCGGGCGGCATAGACGTTCACACGCATGTC GAAACGGTCAGCTTCAACACGCAGTCGGCCGACACGTTCGCAACAGCGACGGTCGCGGCC GCCTGTGGCGGAACGACAACCATCGTCGATTTCTGTCAGCAGGATCGCGGCCACAGCCTG GCGGAAGCCGTCGCCAAGTGGGACGGTATGGCCGGCGGCAAGTCGGCGATCGATTACGGC TACCACATCATCGTGCTCGACCCGACCGACAGCGTGATTGAGGAGCTGGAGGTGCTTCCC GATCTTGGCATTACCTCCTTCAAGGTCTTCATGGCCTATCGCGGCATGAACATGATCGAC GACGTGACGCTGCTGAAGACGCTCGACAAGGCGGTCAAGACCGGATCGCTCGTCATGGTG CACGCGGAAAACGGCGACGCCGCCGACTATCTGCGCGACAAGTTCGTGGCCGAGGGCAAA ACCGCGCCGATCTACCACGCGCTCAGCCGCCCGCCCCGGGTCGAAGCCGAGGCAACCGCG CGGGCCCTCGCCCTGGCCGAAATCGTCAACGCCCCGATCTACATAGTCCATGTGACCTGC GAGGAGTCCCTTGAGGAGGTGATGCGCGCAAAATCGCGAGGCGTCCGCGCTCTGGCGGAA ACCTGCACGCATTACCTTTACCTCACCAAGGAAGACCTGGAGCGGCCGGATTTCGAAGGT GCGAAATACGTTTTCACACCGCCGGCCCGCGCGAAGAAAGACCATGACGTTCTCTGGAAC GCACTCAGAAACGGTGTGTTCGAAACGGTTTCCTCCGACCATTGCTCCTGGCTCTTCAAG GGGCACAAGGACCGGGGCCGGAACGACTTTCGCGCCATCCCGAACGGCGCGCCGGGCGTC GAGGAACGGTTGATGATGGTCTATCAGGGCGTCAACGAAGGCCGGATTTCCCTTACCCAG TTCGTGGAACTGGTCGCCACGCGCCCGGCCAAGGTCTTCGGAATGTTTCCGCAAAAGGGG ACGATCGCGGTCGGTTCGGACGCCGACATCGTCCTTTGGGACCCCGAGGCCGAAATGGTG ATCGAACAGACCGCCATGCACAACGCCATGGATTACTCCTCCTACGAGGGACACAAGGTC AAGGGCGTGCCGAAGACGGTGCTCCTGCGTGGCAAGGTTATCGTCGACGAAGGTTCCTAT GTCGGCGAACCGACGGACGGGAAATTCCTGAAACGTCGCAAATACAAGCAGTAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
Resource Link
UniProtKB ID Q8VTT5
UniProtKB Entry Name HYDA_RALPI
通用电气nBank Protein ID 17224959
通用电气nBank Gene ID AF320814
通用电气neral References
  1. Xu Z, Liu Y, Yang Y, Jiang W, Arnold E, Ding J: Crystal structure of D-Hydantoinase from Burkholderia pickettii at a resolution of 2.7 Angstroms: insights into the molecular basis of enzyme thermostability. J Bacteriol. 2003 Jul;185(14):4038-49. [Article]

Drug Relations

Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details
DB03801 Lysine Nz-Carboxylic Acid experimental unknown Details