Reaction:(2R)-1-(2,6-dimethylphenoxy)propan-2-amineto1 product

Reaction
(2R)-1-(2,6-dimethylphenoxy)propan-2-amine
DB07129
(R)-(-)-Mexiletine, p-hydroxyl
DBMET01551
Reaction type
Aromatic hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Zhou SF: Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II. Clin Pharmacokinet. 2009;48(12):761-804. doi: 10.2165/11318070-000000000-00000. [Article]
  2. Wang B, Zhou SF: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218. [Article]
Comments
Not Available
Enzymes
Enzyme Km Vmax Role
Cytochrome P450 1A2 Not Available Not Available implied
Cytochrome P450 2D6 Not Available Not Available implied