Reaction:Simvastatinto1 product

Reaction
Simvastatin
DB00641
6'-exomethylene
DBMET01747
Reaction type
dehydrogenation
Direction
Major circulating metabolite?
No
Spontaneous?
No
交流tivity
unknown
References
  1. Woodland C, Huang TT, Gryz E, Bendayan R, Fawcett JP: Expression, activity and regulation of CYP3A in human and rodent brain. Drug Metab Rev. 2008;40(1):149-68. doi: 10.1080/03602530701836712 . [Article]
Comments
Not Available
Enzymes
Enzyme Km Vmax Role
Cytochrome P450 3A4 Not Available Not Available implied
Cytochrome P450 3A5 Not Available Not Available implied