Reaction:Codeineto1 product

Reaction
Codeine
DB00318
norcodeine
DBMET00340
Reaction type
N-demethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
交流tivity
unknown
References
  1. Cregg R, Russo G, Gubbay A, Branford R, Sato H: Pharmacogenetics of analgesic drugs. Br J Pain. 2013 Nov;7(4):189-208. doi: 10.1177/2049463713507439. [Article]
  2. Codeine FDA label [File]
Comments
Not Available
Enzymes
Enzyme Km Vmax Role
Cytochrome P450 3A4 Not Available Not Available implied