Dexmethylphenidate hydrochlorideProduct ingredient forDexmethylphenidate
- Name
- Dexmethylphenidate hydrochloride
- Drug Entry
-
Dexmethylphenidate
Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 20022. It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant5. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)Label,2. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture2.
- Accession Number
- DBSALT001458
- Structure
-
Structure for Dexmethylphenidate hydrochloride (DBSALT001458)
- Synonyms
- Dexmethylphenidate HCl
- UNII
- 1678OK0E08
- CAS Number
- 19262-68-1
- Weight
-
Average: 269.77
Monoisotopic: 269.1182566 - Chemical Formula
- C14H20ClNO2
- InChI Key
- JUMYIBMBTDDLNG-OJERSXHUSA-N
- InChI
-
InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H/t12-,13-;/m1./s1
- IUPAC Name
-
methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate hydrochloride
- SMILES
-
Cl.[H][C@@](C(=O)OC)(C1=CC=CC=C1)[C@@]1([H])CCCCN1
- External Links
-
- ChemSpider
- 135806
- ChEMBL
- CHEMBL904
- Wikipedia
- Dexmethylphenidate
- Predicted Properties
-
Property Value Source Water Solubility 0.182 mg/mL ALOGPS logP 1.47 ALOGPS logP 2.25 Chemaxon logS -3.1 ALOGPS pKa (Strongest Basic) 9.09 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 38.33 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 66.73 m3·mol-1 Chemaxon Polarizability 26.15 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon
