Briciclib SodiumProduct ingredient forBriciclib
- Name
- Briciclib Sodium
- Drug Entry
-
Briciclib
Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and Acute Lymphocytic Leukemia.
- Accession Number
- DBSALT002120
- Structure
-
Structure for Briciclib Sodium (DBSALT002120)
- Synonyms
- Not Available
- UNII
- 7C9N0VM8NR
- CAS Number
- 865784-01-6
- Weight
-
Average: 518.38
Monoisotopic: 518.03884361 - Chemical Formula
- C19H21Na2O10PS
- InChI Key
- MIBWXNAYNGADJD-MIIBGCIDSA-L
- InChI
-
InChI=1S/C19H23O10PS.2Na/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22;;/h5-11H,12H2,1-4H3,(H2,20,21,22);;/q;2*+1/p-2/b8-7+;;
- IUPAC Name
-
disodium 2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl phosphate
- SMILES
-
[Na+].[Na+].COC1=CC(OC)=C(\C=C\S(=O)(=O)CC2=CC=C(OC)C(OP([O-])([O-])=O)=C2)C(OC)=C1
- External Links
-
- ChemSpider
- 32058874
- ChEMBL
- CHEMBL3137303
- Predicted Properties
-
Property Value Source Water Solubility 0.36 mg/mL ALOGPS logP 2.34 ALOGPS logP 1.32 Chemaxon logS -3.2 ALOGPS pKa (Strongest Acidic) 1.62 Chemaxon pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 9 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 143.48 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 110.83 m3·mol-1 Chemaxon Polarizability 44.28 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon
